Under exposure to 1% PROCAPIL, 58% more growth than that of the control was obtained and the growth was similar to that observed in the presence of 2 ppm Minoxidil® (10 μM). With 2.5% PROCAPIL, the growth was 121% greater than that of the control
Hairloss treatment review. - by Dr Joel Arun
Dermedics MESOHAIR
Introduction
I was privileged to be offered a trial-set of the Dermedics MESOHAIR Intensive Hair Therapy set 2 weeks ago. This review will aim to provide readers a basic background of the product,
Product Background
MESOHAIR is a serum designed to prevent hair loss, and is indicated for people who are suffering from premature hair loss. It is produced by Dermedics – a Polish beauty company. The company is GMP (Good Manufacturing Practices) compliant, and has also been accorded the CE mark for medical products. These are re-assuring! The MESOHAIR serum does not contain parabens, artificial fragrances, alcohol, colorants or formaldehyde. It is also free of growth factors and hormonal stimulants.
Core Ingredients
MESOHAIR’s active ingredients can be confusing to interpret if one is not familiar with the medical or scientific jargon used. The ingredients are Biotinyl-GHK and Procapil. Biotinyl-GHK is a protein derivative of Biotin (Vitamin B7). Procapil, which itself comprises of Apigenin and Oleanolic Acid together with an extracellular peptide (Matrikine), is the core ingredient of MESOHAIR serum. Apigenin is a naturally occurring plant compound which is subcategorized under a group called glycosides. Oleanolic Acid is also a naturally occurring plant compound which can be found commonly in olive oil and garlic. Ingredient Properties
Biotinyl-GHK: A protein derivate of Vitamin B7; deficiency of which can lead to brittle hair and nails, and in severe cases can lead to dermatitis (rash). Biotin supplementation is routinely recommended in people who suffer from brittle hair or hair loss. Apigenin: A naturally occurring plant compound; it is a glycoside. Found in many natural herbs and plants such as chamomile, parsley and celery.
Oleanolic Acid: A naturally occurring plant compound which is commonly found in olive oil, pokeweed, and garlic. It is non-toxic and has been shown to inhibit 5α-reductase in-vitro. The inhibition of this enzyme is the key mechanism of action in treating male pattern hair loss.
Other Hair Growth Therapies
There are other hair growth therapies which exist in the commercial market, and perhaps the most popular of them all is Minoxidil. Minoxidil was initially developed as an anti-hypertensive (blood pressure lowering) medicine and was incidentally found to have the side effect of unintentional hair growth. Since then, it has been marketed as a hair-growth serum to be applied topically or sprayed. However, a significant proportion of users do report side-effects of itching, burning, dry skin, chest tightness, palpitations, chest pain, dizziness and fainting. Moreover, the initial phase of Minoxidil use may come with temporary hair loss – this is described as “shedding” by some proponents of Minoxidil.
Dr Joel Arun
M.B.B.S (Bachelor of Medicine, Bachelor of Surgery), 2014
National University of Singapore